Molecular Classification of Triple-Negative Breast Cancer
نویسندگان
چکیده
منابع مشابه
Molecular Classification of Triple-Negative Breast Cancer
Tumor heterogeneity of triple-negative breast cancer (TNBC) has been the main barrier in conquering breast cancer. To dissect the molecular diversity of TNBC and discover therapeutic targets for TNBC, the molecular classification of TNBC is a prioritized issue in research area. Accordingly, recent studies have been successful in classifying TNBC into several distinct subtypes with specific biol...
متن کاملClinicopathological Features of Non-metastatic Triple Negative Breast Cancer
Background: Triple negative breast cancer (TNBC) is reported to be associated with a high risk of recurrence, poor overall survival (OS), and disease-free survival (DFS) rates. This study evaluated the clincopathological features and survival of non-metastatic TNBC women in the capital of Iran compared with other areas of the world. Methods: In a retrospective study, 119 women with TNBC based ...
متن کاملtriple negative breast cancer: molecular classification, prognostic markers and targeted therapies
context triple negative breast cancer (tnbc) is a heterogeneous group of diseases that is negative for esterogen receptor (er) progesteron receptor (pr) and human epidermal growth factor receptor 2 (her2). this type of breast cancer is typically high-grade carcinomas, although low-grade tumors occur. the aim of this review is to focus on molecular classification and features, prognostic markers...
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Triple negative breast cancer (TNBC): challenges and solutions via the immune cells TNBC is one of the most complicated types of breast cancer to treat. It is generally diagnosed based on the absence of three receptors: estrogen, progesterone, and human epidermal growth factor receptor 2 (HER2) and is thus defined as a triple negative. TNBC is often more aggressive with lower survival rates...
متن کاملTriple-Negative Breast Cancer
Triple-negative breast cancer, so called because it lacks expression of the estrogen receptor, progesterone receptor, and HER2, is often, but not always, a basal-like breast cancer. This review focuses on its origin, molecular and clinical characteristics, and treatment.
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ژورنال
عنوان ژورنال: Journal of Breast Cancer
سال: 2016
ISSN: 1738-6756,2092-9900
DOI: 10.4048/jbc.2016.19.3.223